January 28, 2010

Test Your Clinical Knowledge!



What is the most appropriate liver test to exclude liver cell failure in a routine work-up in elderly patients, especially patients with dementia?


Posted by A Dakson
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2 comments:

  1. Anonymous30 January 2010 at 03:48

    this is an easy question.. check for elevated liver enzymes ie ALT and AST

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  2. A Dakson30 January 2010 at 16:00

    Hmm.. not a very easy question afterall because liver enzymes indicate structural damage ie hepatocytes rupturing and releasing the enzymes.

    Correct Answer is aldbumin and prothrombin time. If the liver fails to function for any reason even in the absence of structural damage, it also ceases to carry out its functions in as a manufacturer of plasma proteins and coagulation factors. So we end up with a deficiency of these parameters.

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