January 21, 2010

Who needs a transplant when you can grow a new organ?

Posted by Sarah

3 comments:

  1. A Dakson21 January 2010 at 21:56

    very clear, concise and down to the point! thanks, that was really interesting.

    The main challenge as the speaker pointed out is in those organs needing stem cell regenerative methods such as the brain for example. But I was surprised to see the approach works on patients with spina bifida. So that is my friend news to me, I need to find out more:)

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  2. Sarah22 January 2010 at 00:12

    If you are interested in regeneration in the brain I highly recommend this article:

    Nat Rev Neurosci. 2009 Oct;10(10):713-23.
    Considering the evolution of regeneration in the central nervous system.
    Tanaka EM, Ferretti P.

    For many years the mammalian CNS has been seen as an organ that is unable to regenerate. However, it was also long known that lower vertebrate species are capable of impressive regeneration of CNS structures. How did this situation arise through evolution? Increasing cellular and molecular understanding of regeneration in different animal species coupled with studies of adult neurogenesis in mammals is providing a basis for addressing this question. Here we compare CNS regeneration among vertebrates and speculate on how this ability may have emerged or been restricted.

    PMID: 19763104 [PubMed - indexed for MEDLINE]

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  3. A Dakson22 January 2010 at 16:41

    Thank you, I am sure it'll make an entertaining over-the-weekend read!

    ReplyDelete

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